Tetrahedron Letters p. 3073 - 3077 (2017)
Update date:2022-09-26
Topics:
Jacobsen, Eric
Chavda, Mihir K.
Zikpi, Kokou M.
Waggoner, Stephanie L.
Passini, Daniel J.
Wolfe, Jesse A.
Larson, Robert
Beckley, Chelsea
Hamaker, Christopher G.
Hitchcock, Shawn R.
A reagent combination of toluenesulfinic acid and trimethylacetyl chloride affords a putative trimethylacetic p-toluenesulfinic anhydride. This reagent has been used to prepare a series of sulfinate esters from primary and secondary alcohols. In addition, the reagent was used to convert Baylis-Hillman substrates into allylic sulfones. Attempts to use the reagent to convert amines to sulfinamides were unsuccessful. In contrast, the use of 2-pyrrolidinone afforded N-p-toluenesulfinyl pyrrolidinone in 64% yield. The use of a chiral 4-benzyl-1,3-oxazolidinone or 4-benzyl-1,3-oxazolidine-2-thione led to the isolation of S-p-tolyl p-toluenethiosulfonate.
View MoreContact:+86-13666670345
Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Rugao Jinling Chemical Co., Ltd.(expird)
Contact:0086-513-68005586
Address:Lianluo new village huangshi town Rugao city Jiangsu Province.
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.
Contact:+86-576-87501888 / 87501988
Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Contact:+852-8198 2399
Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD
website:http://www.czyys.com
Contact:0086-519-88802789
Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
Doi:10.1021/jo00881a016
(1976)Doi:10.1002/chem.201500331
(2015)Doi:10.1002/jlcr.2590030205
(1967)Doi:10.1039/d0sc01317j
(2020)Doi:10.1023/A:1016259816661
(1995)Doi:10.1021/ol301782s
(2012)