Glycerides as prodrugs. 3. Synthesis and antiinflammatory activity of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides (indomethacin glycerides)

DOI: 10.1021/jm00175a003

Source and publish data:

Journal of Medicinal Chemistry p. 9 - 13 (1980)

Update date:2022-08-05

Topics:

Authors:

Paris Paris

Garmaise

Cimon Cimon

Swett Swett

Carter Carter

Young Young

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Article abstract of DOI:10.1021/jm00175a003

Mono-, bis-, and tris[1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides and 1,3-dialkanoyl-2-[1-p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides were synthesized and evaluated for antiinflammatory activity in the rat paw carrag

Full text of DOI:10.1021/jm00175a003

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