SYNTHESIS OF LH-RH USING A NEW PHENOLIC POLYMER AS SOLID SUPPORT AND "BOP" REAGENT FOR FRAGMENT COUPLING

Article abstract of DOI:10.1016/0040-4020(80)80193-1

p-Hydroxyphenyl propionic resin (Table I, compound 4) was used to prepare the 1-6 protected fragment of LH-RH which was then condensed with "BOP" (benzotriazolyl N-oxytrisdimethylaminophosphonium hexafluorophosphate) as coupling reagent to the 7-10 residu