Bioorganic and Medicinal Chemistry Letters p. 425 - 430 (1999)
Update date:2022-08-04
Topics:
Min, Yong Ki
Asami, Tadao
Fujioka, Shozo
Murofushi, Noboru
Yamaguchi, Isomaro
Yoshida, Shigeo
The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3- (1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.
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