A Novel Oxidation of Internal Alkynes with Hydrogen Peroxide Catalyzed by Peroxotungsten Compounds

Article abstract of DOI:10.1021/jo00308a002

Internal alkynes underwent a novel oxidation with aqueous hydrogen peroxide catalyzed by peroxotungsten compounds under two-phase conditions using chloroform as the solvent, giving α,β-epoxy ketones and α,β-unsaturated ketones as principal products.The epoxidation of α,β-unsaturated ketones by this catalyst-oxidant system appeared to involve the electrophilic attack of the peroxo species to the double bond.