Preparation, Reactions, and Stereochemistry of 4-tert-Butyl-1-chlorophosphorinane 1-Oxide and Derivatives

Article abstract of DOI:10.1021/jo00125a012

The title compound 6 was synthesized as a model structure to study the stereochemical and mechanistic aspects of nucleophilic substitution at the phosphorus atom in a six-membered ring.Several synthetic methods were used to prepare 6, but in every case a