PHASE MANAGED ORGANIC SYNTHESIS 3. SYMMETRICAL ANHYDRIDES FROM CARBOXYLIC ACIDS VIA POLYMER ASSISTED REACTION.

Article abstract of DOI:10.1016/S0040-4039(00)85101-1

Symmetrical anhydrides are produced quickly and in high yield by treating mixtures of a carboxylic acid and one-half equivalent thionyl chloride in dichloromethane with a solid-state copolymer of 4-vinylpyridine.This conversion is accomplished equally well in batch or column mode.