Total Synthesis of (+/-)-Prostaglandin I2 Methyl Ester and (+/-)-15-epi-Prostaglandin I2 Methyl Ester

DOI: 10.1039/c39810000922

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 922 - 924 (1981)

Update date:2022-08-03

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Authors:

Newton, Roger F.

Roberts, Stanley M.

Wakefield, Basil J.

Woolley, Geoffrey T.

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Article abstract of DOI:10.1039/c39810000922

Prostacyclin (prostaglandin I₂) methyl ester has been prepared; the key step was an aldol reaction between a cyclopentanone enolate and the cyclopentenylacetaldehyde derivative (4).

Full text of DOI:10.1039/c39810000922

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