Microwave assisted sulfopropylation of N-heterocycles using 1,3-propane sultone

DOI: 10.1016/S0040-4039(98)02301-6

Source and publish data:

Tetrahedron Letters p. 9587 - 9588 (1998)

Update date:2022-08-05

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Authors:

Adamczyk, Maciej

Rege, Sushil

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Article abstract of DOI:10.1016/S0040-4039(98)02301-6

Dramatic rate acceleration was observed for N-sulfopropylation of heterocyclic compounds (1a-h) using 1,3-propane sultone(2) under microwave irradiation affording the N-sulfopropylated compounds (3a-h) in 68-95% yield.

Full text of DOI:10.1016/S0040-4039(98)02301-6

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