Synthetic Communications p. 2605 - 2611 (2003)
Update date:2022-08-05
Topics: Synthesis
Chang, HeXi
Ensinger, Carol
McCargar, Robert D.
Vittimberga, Bruno M.
The o-nitrobenzyl group, possessing distinct advantage of being photolabile under mild conditions, was successfully connected to 8-(5,6-epoxynorbornan-2-yl)-1,3-dipropylxanthine (5), a high specific A1 adenosine receptor antagonist. The resulting compound 4 would have potential use as a prodrug.
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(2002)