Organic Letters p. 4627 - 4630 (2003)
Update date:2022-08-04
Topics:
Slater, Martin J.
Amphlett, Elizabeth M.
Andrews, David M.
Bamborough, Paul
Carey, Seb J.
Johnson, Martin R.
Jones, Paul S.
Mills, Gail
Parry, Nigel R.
Somers, Donald O'N.
Stewart, Alan J.
Skarzynski, Tadeusz
(Matrix presented) In this, the first of two Letters, we describe how a P3/P4 urea linking unit was used to greatly enhance the biochemical and replicon potency of inhibitors based upon the pyrrolidine-5,5-trans-lactam template. Compound 7b demonstrated a
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Doi:10.1007/BF00480666
()Doi:10.1016/S0040-4039(01)93085-0
(1977)Doi:10.1021/ma035337a
(2004)Doi:10.1016/S0022-328X(00)80878-5
(1978)Doi:10.1016/j.tetlet.2012.03.115
(2012)Doi:10.1007/s12039-011-0114-3
(2011)
