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NaBH4 and tartaric acid. However, enantioselectivity and
product yield were moderate. We then utilized Braun’s
acetate aldol reaction to construct the C18-sterogenic center
efficiently. Further work toward the total synthesis of
FR252129 is in progress.
Acknowledgments
Financial support by the National Institutes of Health and
Purdue University is gratefully acknowledged.
Supplementary Data
Supplementary data associated with this article can be found
in the online version.
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