Journal of Medicinal Chemistry p. 336 - 341 (1981)
Update date:2022-07-30
Topics:
Ciganek, Engelbert
Uyeda, Roy T.
Cohen, Marvin
Smith, Dewey H.
Analogues of tricyclic antidepressants were synthesized in which the α-carbon of the side chain was replaced by nitrogen.The antidepressant activity of these imines, as measured by the reversal of the effects of tetrabenazine in mice, showed a structure-a
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