Sterically Hindered Lithium Dialkylamides; A Novel Synthesis of Lithium Dialkylamides from N-t-Alkyl-N-benzylideneamines and the Isolation of Highly Hindered s-Alkyl-t-alkylamines

DOI: 10.1055/s-1985-31452

Source and publish data:

Synthesis p. 1138 - 1140 (1985)

Update date:2022-08-03

Topics: Synthesis Isolation Reactivity Steric hindrance Deprotonation Schiff Base Metalation Lithium dialkylamides Organolithium Reagents

Authors:

Cliffe, Ian A.

Crossley, Roger

Shepherd, Robin G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1985-31452

The convenient synthesis of lithium amides from imines 1 and organolithium reagents, and the isolation of the related highly hindered dialkylamines 3 are described.

Full text of DOI:10.1055/s-1985-31452

Products guided by the article

Product name:N-Benzylidene-t-amylamine

Cas No:65815-57-8

R&D Labs maybe for 65815-57-8

Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
Sigma-Aldrich Chemie GmbH

website:http://www.sigmaaldrich.com

Contact:800 558-9160

Address:Industriestrasse 25CH-9471 Buchs SGSwitzerland
Shanghai agrotree chemical co.,ltd.

Contact:+86-21-50117563

Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai

Relevant to this article

Contribution to the asymmetric synthesis of bicyclic compounds catalysed by optically active amino acids. Synthesis of (S)-2-pyrrolidinepropionic acid and (R)-4-amino-5-phenylvaleric acid

Doi:10.1002/hlca.19770600826
(1977)
Copper(II) triflate as a source of triflic acid: effective, green catalysis of hydroalkoxylation reactions

Doi:10.1002/adsc.200800750
(2009)
Atom Economic Ruthenium-Catalyzed Synthesis of Bulky β-Oxo Esters

Doi:10.1002/adsc.201500712
(2015)
Preparation of highly substituted 4-aminopyridones via the reaction of 2-methylene dihydrobenzimidazole with vinyl isocyanates

Doi:10.1021/ol034263k
(2003)
A NEW METHOD FOR THE HYDROXYMETHYLATION OF CARBONYL COMPOUNDS

Doi:10.1016/S0040-4039(01)91015-9
(1984)
Synthesis of the two main urinary tetranor metabolites of 15-F_2t-isoprostane

Doi:10.1016/S0040-4039(01)00754-7
(2001)

Article Doi