Antimycotic azoles. 7. Synthesis and antifungal properties of a series of novel triazol-3-ones

DOI: 10.1021/jm00373a015

Source and publish data:

Journal of Medicinal Chemistry p. 894 - 900 (1984)

Update date:2022-09-26

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Authors:

Heeres Heeres

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Van Cutsem

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Article abstract of DOI:10.1021/jm00373a015

A series of novel triazol-3-ones has been synthesized, and their in vitro and in vivo antifungal properties are reported. Traconazole. which displays a pronounced oral activity against vaginal candidosis in rats and against microsporosis in guinea pigs, has been selected for clinical evaluation.

Full text of DOI:10.1021/jm00373a015

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