Synthesis and Immunoadjuvant Activities of 2-Acetamido-5-O-acetyl-6-O-acyl-2-deoxy-3-O--D-glucofuranoses as Potential Prodrug Forms of 6-O-Acyl Derivatives of N-Acetylmuramyl Dipeptide

Article abstract of DOI:10.1021/jm00351a005

2-Acetamido-5-O-acetyl-6-O-acyl-2-deoxy-3-O-<(R)-2-propionyl-L-alanyl-D-isoglutamine>-D-glucofuranoses, designed as prodrug forms of the corresponding immunoadjuvant-active 6-O-acyl derivatives of N-acetylmuramyl dipeptide (MDP), were synthesized from ben