Tetrahedron p. 13 - 28 (1993)
Update date:2022-07-31
Topics:
Funabashi
Tsubotani
Koyama
Katayama
Harada
The chemical structure of a new dipeptide antibiotic, TAN-1057 A, isolated from the broth filtrate of Flexibacter sp. PK-74 was determined to be (3'S, 5S)-5-[N-methyl-N-(3'-amino-6'-guanidinohexanoyl)amino]-5,6-dihydro-2- ureido-4(1H) pyrimidone. The antibiotic was specifically active against staphyloccocus species including methicillin-resistant strains.
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