Structure-activity relationships of dimeric Catharanthus alkaloids. 2. Experimental antitumor activities of N-substituted deacetylvinblastine amide (vindesine) sulfates

DOI: 10.1021/jm00190a008

Source and publish data:

Journal of Medicinal Chemistry p. 391 - 400 (1979)

Update date:2022-07-31

Topics:

Authors:

Conrad Conrad

Cullinan

Gerzon Gerzon

Poore Poore

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Article abstract of DOI:10.1021/jm00190a008

While structure-activity relationships for vinblastine (VLB), vincristine, deacetyl-VLB, and deacetyl-VLB amide (vindesine, VDS) in several tumor and leukemia models have been reported previously, the present study explores these relationships for a serie

Full text of DOI:10.1021/jm00190a008

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