Tetrahedron p. 5287 - 5304 (1998)
Update date:2022-08-04
Topics:
Audouin, Max
Cortez, Julia Bocanegra de
Hamon, Louis
Levisalles, Jacques
Platzer, Nicole
Synthesis of p-toluenesulfonates 8b and 9b and of labelled analogs is described and previous assignements of proton NMR signals for quaternary methyl groups are confirmed. Acetolysis of these p-toluenesulfonates in the presence of NaOAc gave both substitution and elimination products. Substitution could be accounted for by bimolecular processes (SN2 on carbon, SAN on sulfur). Kinetics confirmed the intervention of bimolecular processes for 8b. Elimination products came for a great part from intermediates formed by hydride and/or methyl shifts. All rearranged products could be explained by plain sigmatropic rearrangements or by contact ion pair rearrangements. Attention is drawn to the close resemblance between sigmatropic rearrangements and contact ion pair rearrangements.
View MoreMelone Pharmaceutical Co., ltd
Contact:+86-411 82593920, 82593631
Address:No 232, JInma Roda, Development Zone, Dalian, China
Contact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Suzhou Kangrun Pharmaceutical, Inc
Contact:86-512-63912376，63913329
Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
website:http://www.dulynet.com/
Contact:025-84699383 -8003
Address:Room 503, Building 2, Chuangxinhui, No. 61 Wenjing Road, High-tech Development Zone, Pukou District, Nanjing City, Jiangsu Province Nanjing, Jiangsu
Quhua Zhongxing Refrigeration Technology Co.,Ltd.
Contact:+86-5708886618
Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Doi:10.1016/j.bmcl.2017.10.018
(2017)Doi:10.1016/S0014-827X(99)00083-X
(1999)Doi:10.1021/ol300810p
(2012)Doi:10.1016/j.saa.2012.02.096
(2012)Doi:10.1039/c2cc31394d
(2012)Doi:10.1016/j.ejmech.2012.02.047
(2012)
