Synthesis and Conformational Studies of a β-Turn Mimetic Incorporated in Leu-enkephalin

DOI: 10.1021/jo0356863

Source and publish data:

Journal of Organic Chemistry p. 3500 - 3508 (2004)

Update date:2022-08-02

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Authors:

Blomberg, David

Hedenstroem, Mattias

Kreye, Paul

Sethson, Ingmar

Brickmann, Kay

Kihlberg, Jan

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Article abstract of DOI:10.1021/jo0356863

A β-turn mimetic in which the four amino acids of a β-turn have been replaced by a 10-membered ring has been designed, synthesized, and subjected to conformational studies. In the mimetic, the intramolecular CO _i - HN_i+3 hydrogen bon

Full text of DOI:10.1021/jo0356863

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