Inhibition studies with rationally designed inhibitors of the human low molecular weight protein tyrosine phosphatase

Article abstract of DOI:10.1016/j.bmc.2004.01.042

The human low molecular weight protein tyrosine phosphatase (HCPTP) is ubiquitously expressed as two isoforms in a wide range of human cells and may be involved in regulating the metastatic nature of epithelial tumors. A homology model is presented for th