A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor

DOI: 10.1021/jm034249d

Source and publish data:

Journal of Medicinal Chemistry p. 2973 - 2976 (2004)

Update date:2022-08-04

Topics:

Authors:

Zaveri, Nurulain T.

Jiang, Faming

Olsen, Cris M.

Deschamps, Jeffrey R.

Parrish, Damon

Polgar, Willma

Toll, Lawrence

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Article abstract of DOI:10.1021/jm034249d

A series of N-(4-piperidinyl)-2-indolinones were discovered as a new structural class of nociceptin receptor (NOP) ligands. Unlike other previously reported classes of NOP receptor ligands, modifications of the piperidine N substituents afforded both pote

Full text of DOI:10.1021/jm034249d

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