An environmentally benign synthesis of cis-2,6-disubstituted tetrahydropyrans via indium-mediated tandem allylation/prins cyclization reaction

DOI: 10.1021/jo7016857

Source and publish data:

Journal of Organic Chemistry p. 741 - 744 (2008)

Update date:2022-08-04

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Authors:

Pham, Minh

Allatabakhsh, Amir

Minehan, Thomas G.

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Article abstract of DOI:10.1021/jo7016857

(Chemical Equation Presented) In the presence of indium metal, 3-iodo-2-[(trimethylsilyl)-methyl]propene (1) reacts with sequentially added aldehydes to provide cis-2,6-disubstituted tetrahydropyrans in good yields. Evidence suggests that InI, formed upon

Full text of DOI:10.1021/jo7016857

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