Journal of the Chemical Society, Dalton Transactions p. 289 - 296 (1994)
Update date:2022-08-05
Topics:
David, Dorothy M.
Kane-Maguire, Leon A. P.
Pyne, Stephen G.
A range of imine complexes has been prepared which possess planar chirality associated with the attached tricarbonyl(1,2-disubstituted arene)chromium moiety.Nucleophilic addition to the imine group of these complexes occurs with high diastereoselectivity, providing an efficient route to the asymmetric synthesis of chiral amines.The stereochemical outcome of the additions may be rationalized in terms of a favoured conformer for the complexes, with nucleophilic attack occurring on the face of the imine anti to the sterically demanding Cr(CO)3 group.Related studies have also been carried out on imine complexes in which the chiral auxiliary is instead a carbon centre attached to the imine N atom.In these latter systems high diastereoselectivity was also observed, but was not superior to that achieved with the related free amines.
View Morewebsite:http://www.alwaychem.com
Contact:+86-532-8586-4000, 8586-5000
Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
jiangsu hualin chemical co.,ltd.
Contact:86-25-87787402
Address:jaingsu,china
Beijing Tianjia Chemical Science & Technology Co.,Ltd
Contact:86-0550-2392698
Address:No.388, Shiliang Road (East),
Nantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Jiaxing Taixin Pharmaceutical Chemical Co., Ltd
Contact:0573-82613601
Address:Chemical Park, Jiaxing, Zhejiang, China
Doi:10.1021/jo01334a009
(1979)Doi:10.1021/ja00508a042
(1979)Doi:10.1016/j.jorganchem.2004.02.025
(2004)Doi:10.1016/S0031-9422(00)84138-2
(1984)Doi:10.1021/jo00118a046
(1995)Doi:10.1016/S0020-1693(00)93422-4
(1979)
