Synthesis of (+)-(4S)- and (-)-(4R)11 Z-4-hydroxyretinals and determination of the absolute stereochemistry of a visual pigment chromophore in the bioluminescent squid, Watasenia scintillans

Article abstract of DOI:10.1016/S0040-4039(00)75995-8

Synthesis of (+)-(4S)- and (-)-(4R)-11Z-4-hydroxyretinals (4-OH-RALs) 1a and 1b was accomplished from (4S)- and (4R)-4-hydroxy-β-ionones, respectively, to determine the absolute configuration of a visual pigment chromophore in Watasenia scintillans. The C