Design, synthesis, and biological activity of novel 4-(3,4-dimethoxyphenyl) -2-methylthiazole-5-carboxylic acid derivatives

Article abstract of DOI:10.1016/j.bmc.2004.03.050

Novel 4-(3,4-dimethoxyphenyl)-2-methylthiazole-5-carboxylic acid derivatives (11-23) were synthesized from 3,4-dimethoxyacetophenone (5) in six-step procedure. Their biological activities were evaluated in the greenhouse. Some of the compounds had shown f