Aminoglycoside antibiotics. 3. Epimino derivatives of neamine, ribostamycin, and kanamycin B

Article abstract of DOI:10.1021/jm00175a009

2',3'-Epimino analogues of neamine, ribostamycin, and kanamycin B possessing little or no intrinsic antimicrobial activity were designed to enhance the activity of kanamycin A against bacterial strains that elaborate aminoglycoside 3'-phosphotransferases.