Modification of the 5' Position of Purine Nucleosides. 2. Synthesis and Some Cardiovascular Properties of Adenosine-5'-(N-substituted)carboxamides

DOI: 10.1021/jm00177a021

Source and publish data:

Journal of Medicinal Chemistry p. 313 - 319 (1980)

Update date:2022-08-05

Topics:

Authors:

Prasad, Raj Nandan

Bariana, Dilbagh S.

Fung, Anthony

Savic, Milica

Tietje, Karin

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00177a021

We have shown previously that the esters of adenosine-5'-carboxylic acid (10) represent a new class of potent nontoxic coronary vasodilators.For example, the ethyl ester (12), which is active by an intraduodenal or intravenous route in dogs, causes a larg

Full text of DOI:10.1021/jm00177a021

Products guided by the article

Product name:(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-N-[2-hydroxy-3-(naphthalen-1-yloxy)propyl]tetrahydrofuran-2-carboxamide (non-preferred name)

Cas No:72758-49-7

R&D Labs maybe for 72758-49-7

Suzhou SuKaiLu Chemical Technology Co., Ltd.

Contact:+86-512-62766020

Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Angelisun(Chongqing) Pharmaceutical Co., LTD.

Contact:+86-23-68030926-816

Address:D1-7 Tech & Entrepreneurs Park, Kecheng Road, Erlang Hi-Tech Areas, Chongqing, China
Hangzhou Haichem Co.,Ltd.

Contact:+86-571-86025531 / 86024803

Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
YanCheng LongShen Chemical Co.,Ltd.

Contact:+86-515-86668866

Address:No.13,Weiyi Road,Funing Aoyang Industrial Park

Relevant to this article

A novel pyrazolopyridine with in vivo activity in Plasmodium berghei- and Plasmodium falciparum-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyridazines

Doi:10.1021/acs.jmedchem.5b01605
(2015)
Tellurium tetrachloride: an improved method of preparation

Doi:10.1016/j.tetlet.2008.02.085
(2008)
Cl3CCONH2/PPh3: A versatile reagent for synthesis of esters

Doi:10.1080/00397910801979361
(2008)
Electrochemical Regioselective Phosphorylation of Nitrogen-Containing Heterocycles and Related Derivatives

Doi:10.1002/adsc.202000997
(2021)
Doi:10.1246/bcsj.52.3765
(1979)
A Method for Transfer of Labeled Methyl Groups

Doi:10.1021/jo01297a038
(1980)

Article Doi