Stereochemical Course of the Haworth-Type Synthesis of Optically Active 2-(1-Methylpropyl)naphthalene

Article abstract of DOI:10.1021/jo01301a007

The preparation of (S)-2-(1-methylpropyl)naphthalene has been accomplished by starting from (S)-(1-methylpropyl)benzene with detectable racemization.The partially unstereospecific steps have been distinguished by evaluating the optical purity of key intermediates through chemical correlations with known optically active compounds.