Canadian Journal of Chemistry p. 939 - 941 (1982)
Update date:2022-08-05
Topics: Structures Pharmacological Properties Bioactivity Isolated
Pettit, George R.
Cragg, Gordon M.
Gust, Devens
Brown, Peter
Schmidt, Jean M.
A new antineoplastic glycoside, phyllanthostatin 1, and the related glycoside, phyllanthoside, have been isolated from the Central American tree, Phyllanthus acuminatus Vahl.The structures of phyllanthostatin (1a) and phyllasthoside (1b) were completely assigned by analyses of spectral data, principally by high resolution (400 MHz) nmr.In addition to exhibiting activity against the National Cancer Institute's P388 lymphocytic leukemia, phyllanthoside was found to possess a curative level of activity against the murine B16 melanoma.
View Morejiangsu hualin chemical co.,ltd.
Contact:86-25-87787402
Address:jaingsu,china
Contact:+86-10-83993285
Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Shanghai ZaiQi Bio-Tech Co., Ltd.,
Contact:+86-21-5482 4098
Address:Bldg. No.7, No.201 MinYi Rd，Songjiang CaoHeJing High-Tech Park Shanghai 201516 P,R,China
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
website:http://www.shydtec.com
Contact:86-21-57721279
Address:Science and Technology Park, Songjiang District, Shanghai, China
Shanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Doi:10.1021/jo01310a004
(1980)Doi:10.1021/ja00528a027
(1980)Doi:10.1021/jm010145w
(2001)Doi:10.1002/hlca.19870700224
(1987)Doi:10.1016/S0040-4039(00)78836-8
(1980)Doi:10.1002/anie.201310193
(2014)
