Journal of the Chemical Society. Chemical communications p. 101 - 102 (1980)
Update date:2022-08-04
Topics:
Kiso, Yoshiaki
Ukawa, Kazuko
Akita, Tadashi
The N-benzyloxycarbonyl group can be smoothly cleaved under mild conditions, using thioanisole-trifluoroacetic acid, which can deprotect O-benzyltyrosine without the formation of O-to-C rearrangement products; this deblocking method was successfully applied to the synthesis of Met-enkephalin.
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(1960)Doi:10.1021/ac052105w
(2006)Doi:10.1021/acs.orglett.8b00353
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(1980)
