Journal of Pharmaceutical Sciences p. 709 - 710 (1978)
Update date:2022-08-03
Topics:
Foster
4 Ethoxycarbonyl analogs of cyclophosphamide and its five-membered ring homolog were synthesized utilizing the cyclization method previously described. N,N Bis(2 chloroethyl) 4 ethoxycarbonyl 1,3,2 oxazaphospholidin 2 amine 2 oxide demonstrated activity against L 1210 lymphoid leukemia whereas N,N bis(2 chloroethyl) 4 (ethoxycarbonyl)tetrahydro 2H 1,3,2 oxazaphosphorin 2 amine 2 oxide did not. The oxazaphosphorin 2 amine was evaluated against human epidermoid carcinoma of the nasopharynx (cell culture). The results again were negative: ED50=2.8x10.
View MoreShanghai Yudiao Chemistry Technology Co.,Ltd
Contact:0086-18964703211
Address:Building NO.5, NO.218,Rongtian Road,ganxiang town,Jinshan District,shanghai,201518,china
Contact:+65 9658 0999
Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Contact:0086-357-6662688
Address:Zhaocheng town, Hongtong County, Linfen City, Shanxi Province
Luoyang Aoda chemical Co.,Ltd.
Contact:+86-379-67518785 67516588
Address:MiaoWan industry district,YanShi City,Henan,China
Shanghai Hongbang Medical Technology CO.,. Ltd
Contact:13671516988 /18917636693
Address:Room1, No67 Building, Yongde Road369, Wujing Town, Minhang Districy, Shanghai CIty, China.
Doi:10.1039/P19800001477
(1980)Doi:10.1007/BF00958823
(1980)Doi:10.1002/ardp.19803130808
(1980)Doi:10.1016/0040-4039(80)80028-1
(1980)Doi:10.1021/ic50215a049
(1981)Doi:10.1016/S0040-4039(00)01309-5
(2000)
