Qualitative and quantitative analysis of small amine molecules by MALDI-TOF mass spectrometry through charge derivatization

Article abstract of DOI:10.1021/ac035537k

A pair of isotopically coded light and heavy reagents, tris-(2,4,6- trimethoxyphenyl)phosphonium acetic acid-N-hydroxysuccinimide esters (1 and 2) were synthesized and used to derivatize low molecular weight (<500 Da) molecules containing primary or secon