Tetrahedron p. 2683 - 2690 (1998)
Update date:2022-09-26
Topics:
Nemoto, Takayuki
Ojika, Makoto
Takahata, Yoshinori
Andoh, Toshiwo
Sakagami, Youji
The structures of topostins, a novel type of mammalian DNA topoisomerase I inhibitors isolated from the bacterium Flexibacter topostinus sp. nov., have remained unknown. Reexamination of the production of topostins resulted in the isolation of original topostins B (B553 (1) and B567 (2)) and new related compounds named topostins D (D640 (3) and D654 (4)). Their structures, including the absolute stereochemistry, were determined by spectroscopic analyses and chemical degradations. These substances are lipid-containing amino acids and peptides.
View MoreHangzhou Gangjin Chemical Co.,Ltd.(expird)
Contact:+86-571-85109780
Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd
Contact:(86) 519-88782201 88784080 88785278
Address:Henglin town, changzhou,Jiangsu
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.
Contact:+86-21-64891143
Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Contact:0086 371 65711996
Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Taizhou KEDE Chemical.Co.,Ltd.
Contact:86-576-84613060
Address:Jiangkou Chemical Zoon
Doi:10.1016/j.tca.2019.03.006
(2019)Doi:10.1021/ja00190a023
(1989)Doi:10.1021/jo00320a025
(1981)Doi:10.1002/ejoc.201700453
(2017)Doi:10.1016/S0040-4039(00)80449-9
(1988)Doi:10.1021/jo00326a039
(1981)
