
Tetrahedron Letters p. 1393 - 1396 (1980)
Update date:2022-08-04
Topics: Synthesis Catalyst Efficient Experimental biologically active 1,2,3,4-tetrahydroisoquinolines
Mendelson, W. L.
Spainhour, C. B.
Jones, S. S.
Lam, B. L.
Wert, K. L.
A new synthesis of tetrahydroisoquinolines bearing electron withdrawing groups is presented.The scope and mechanism of the reaction are discussed.Many of these tetrahydroisoquinolines are potent inhibitors of the enzyme PNMT.
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Doi:10.1039/DT9800001228
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