Phenylselenoetherification. A Highly Efficient Cyclization Process for the Synthesis of O- and S-Heterocycles

Article abstract of DOI:10.1021/ja00531a020

Phenylselenoetherification, a new cyclization procedure based on organoselenium chemistry, is described in detail.Unsaturated hydroxy and thio compounds were subjected to this new cyclization process to afford a series of phenyl selenoethers and phenyl selenothioethers which were transformed to a variety of heterocyclic systems by reductive or oxidative removal of the selenium group.Applications to the synthesis of muscarine analogues are described.