Stereodivergent total asymmetric synthesis of polyhydroxylated pyrrolidines via tandem allylic epoxidation and intramolecular cyclization reactions

Article abstract of DOI:10.1016/j.tetlet.2004.06.048

Epoxidation of the allylic alcohols 10 and 11 using the VO(acac) ₂/t-BuOOH system followed by an intramolecular 5-exo cyclization of the resulting δ-epoxycarbamates 12, 13, 18, and 19 has been shown to provide a general and efficient solution f