Efficient Stereocontrolled Total Syntheses of Racemic and Natural Brefeldin-A

DOI: 10.1021/ja00384a038

Source and publish data:

Journal of the American Chemical Society p. 5473 - 5483 (1982)

Update date:2022-09-26

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Authors:

Drian, Claude Le

Greene, Andrew E.

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Article abstract of DOI:10.1021/ja00384a038

Brefeldin-A, an antiobiotic fungal metabolite, has been obtained in both racemic and natural forms through a direct approach that employs norbornenone and 6-heptyn-2-ol as the basic starting materials.

Full text of DOI:10.1021/ja00384a038

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