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Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters

DOI: 10.1016/j.bmcl.2006.07.070

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 5018 - 5021 (2006)

Update date:2022-09-26

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Authors:

Zheng, GuangrongZheng, Guangrong

Horton, David B.Horton, David B.

Deaciuc, Agripina G.Deaciuc, Agripina G.

Dwoskin, Linda P.Dwoskin, Linda P.

Crooks, Peter A.Crooks, Peter A.

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Article abstract of DOI:10.1016/j.bmcl.2006.07.070

A series of des-keto lobeline analogs has been synthesized and evaluated for their ability to inhibit the dopamine transporter (DAT) and serotonin transporter (SERT) function and for their affinity for the synaptic vesicle monoamine transporter (VMAT2), a

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Full text of DOI:10.1016/j.bmcl.2006.07.070

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