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The Mechanism of Trifluoroacetylation of Indoles

DOI: 10.1039/P29820000523

Source and publish data:

Journal of the Chemical Society. Perkin transactions II p. 523 - 530 (1982)

Update date:2022-09-26

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Authors:

Cipiciani, AntonioCipiciani, Antonio

Clementi, SergioClementi, Sergio

Giulietti, GianfrancoGiulietti, Gianfranco

Marino, GianlorenzoMarino, Gianlorenzo

Savelli, GianfrancoSavelli, Gianfranco

Linda, PaoloLinda, Paolo

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Article abstract of DOI:10.1039/P29820000523

The mechanism of the reaction between substituted indoles and trifluoroacetic anhydride has been studied by product identification and n.m.r. spectroscopy.Experimental evidence is given for the stability of an ion pair intermediate.

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