Journal of Organic Chemistry p. 4025 - 4031 (1987)
Update date:2022-08-04
Topics:
Cannone, P.
Bernatchez, M.
The study of the reactions of 1,4-bis(bromomagnesio)pentane, 1,1-bis(bromomagnesio)hexane, 1,4-bis(bromomagnesio)heptane, and 1,4-bis(bromomagnesio)octane with aliphatic and aromatic carboxylic acid esters in tetrahydrofuran solution was undertaken in order to ascertain which factors influence isomer distribution.The yields of this annelation processes are in the range of 68-88percent.The formation of trans OH 1,2-disubstituted cyclopentanols having the alkyl groups cis is generally observed with yields of 77-96percent.The reaction of 1,5-bis(bromomagnesio)hexane with carboxylicacid esters is less stereoselective and is more influenced by steric effects.
View MoreJIN TAN CHENG'EN CHEMICAL CO.,LTD.
Contact:86-519-82116250
Address:NO.102,village Dongfang,conomic development zone
Zhangjiagang Jianing Import & Export Co.,Ltd.
Contact:086-512-55379012 13913607595
Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Contact:86-18051083338
Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China
Contact:
Address:308# dongwu avenue dongxihu district wuhan city
Contact:+86-710-3516804
Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei
Doi:10.1039/c9cc09093b
(2020)Doi:10.1039/jr9620004072
(1962)Doi:10.1002/jps.2600761017
(1987)Doi:10.1021/jm500497v
(2014)Doi:10.1007/s00706-012-0800-y
(2013)Doi:10.1002/anie.201500486
(2015)