
Bulletin of the Chemical Society of Japan p. 3273 - 3275 (1980)
Update date:2022-08-02
Topics:
Ohsawa, Akio
Abe, Yoshihito
Igeta, Hiroshi
3-(Dialkylamino)indolizines were synthesized in one step by the reaction of 2-bromopyridine, propargyl alcohol, and secondary amines in the presence of Pd(PPh3)2Cl2-CuI as a catalyst. 3-(2-Pyridyl)-2-propyn-1-ol and 3-(2-pyridyl)acrylaldehyde were suggested to be intermediates of the reaction. 3-Dialkylamino derivatives of pyrrolo<1,2-a>quinoline, pyrrolo<2,1-a>isoquinoline, and pyrrolo<1,2-b>pyridazine were obtained from the corresponding α-haloazaaromatics in a similar way.
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Doi:10.1246/cl.1980.1553
(1980)Doi:10.1055/s-1980-29221
(1980)Doi:10.1016/S0040-4039(00)61883-X
(1985)Doi:10.1016/0040-4020(80)80120-7
(1980)Doi:10.1002/hlca.19800630721
(1980)Doi:10.1016/S0040-4039(01)81921-3
(1981)