Journal of Organic Chemistry p. 2280 - 2286 (1981)
Update date:2022-08-04
Topics:
Austin, William B.
Bilow, Norman
Kelleghan, William J.
Lau, Kreisler S. Y.
The coupling reaction between an aromatic halide and ethynyltrimethylsilane under the catalysis of palladium(0) generated in situ, followed by treatment of the (trimethylsilyl)ethynyl product with potassium carbonate in methanol at ambient temperatures, provides a simple approach to various ethynylated benzoic acid derivatives and other aromatic compounds.The conditions for the removal of the trimethylsilyl group were very mild, so that base-sensitive functionalities on the aromatic moiety could be tolerated.
View MoreContact:+86-571-86025531 / 86024803
Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Dezhou Longteng Chemical Co., Ltd.
website:http://www.sodium-methoxide.cn/
Contact:0086-18866052283
Address:Xinhua Industrial Zone, Dezhou City, Shandong Province, China
Dalian RSD International Trade Co.,Ltd.(expird)
Contact:86-22-60875058 58610575
Address:Wantong International Areas, Hongqiao District, Tianjin, China.China
Contact:0550-7041128 0550-7090578
Address:Wangdian Street,Xinjie Town
Synchem Pharma Co.,Ltd(expird)
Contact:+0086-21-61984905-1
Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Doi:10.1002/ardp.19863190606
(1986)Doi:10.1016/S0040-4039(00)93673-6
(1980)Doi:10.1021/ja00397a039
(1981)Doi:10.1016/S0040-4039(99)01955-3
(1999)Doi:10.1021/ol048946r
(2004)Doi:10.1002/adsc.201700234
(2017)
