Synthesis and Stereochemistry of 2,3,4,6-Tetra-O-benzyl-D-glucopyranosylidene Acetals of α-Diols and Monosaccharides

Article abstract of DOI:10.1246/bcsj.53.3687

The title compounds were synthesized by addition of 2,3,4,6-tetra-O-benzyl-D-glucono-1,5-lactone to epoxides and by direct dehydration between the lactone and diols in the presence of concentrated sulfuric acid as a catalyst.Stereochemistry of these spiro cyclic acetals was discussed.