Synthesis and characterization of iodoazidobenzylpindolol

Article abstract of DOI:10.1002/jps.2600710310

A high affinity β-adrenergic ligand, iodoazidobenzylpindolol, was synthesized and characterized. The absorption spectrum of this compound changed markedly upon photolysis consistent with decomposition of the azide group. This compound has a K(D) of 5-7 x 10^-10M for the duck erythrocyte ghost β-adrenergic receptor when measured in a competitive binding assay.