Synthesis of clozapine analogues and their affinity for clozapine and spiroperidol binding sites in rat brain

Article abstract of DOI:10.1021/jm00141a001

Analogues of clozapine, some prepared by a novel, shorter synthesis than those described previously, were evaluated as potential antipsychotic agents using clozapine binding sites in rat forebrain that are nonmuscarinic and nondopaminergic in nature and f