Identification of an Acridine Photoaffinity Probe for Trypanocidal Action

DOI: 10.1021/jm00373a010

Source and publish data:

Journal of Medicinal Chemistry p. 865 - 870 (1984)

Update date:2022-08-05

Topics:

Authors:

Firth, William J.

Messa, Andrew

Reid, Robert

Wang, Rung Chou (Charles)

Watkins, Charles L

Yielding, Lerena W.

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Article abstract of DOI:10.1021/jm00373a010

Twenty-four acridine derivatives were screened for trypanocidal activity in Trypanosoma brucei in order to determine which structural features of the acridine molecule confer maximal antiparasitic activity.The syntheses of several new azidoacridine deriva

Full text of DOI:10.1021/jm00373a010

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