Journal of Medicinal Chemistry p. 2919 - 2928 (1992)
Update date:2022-09-26
Topics: Synthesis in vivo Biological Activity Conformational constraints CCK Heptapeptide Analogues Standard Modifications Receptor Subtype Selectivity Functional Activity in Vitro Appetite Suppression
Holladay, Mark W.
Bennett, Michael J.
Tufano, Michael D.
Lin, C. W.
Asin, Karen E.
et al.
A series of modifications of the CCK7 analogue (des-NH2)Tyr(SO3-)-Nle-Gly-Trp-Nle-Asp-Phe-NH2 was prepared and tested for binding to guinea pig CCK-A and CCK-B receptors and in CCK-A-mediated functional assays.Selected analogues also were teste
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(2021)Doi:10.1039/P19830001417
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