Synthesis of C2-symmetric HIV-protease inhibitors with sulfur-containing central units

Article abstract of DOI:10.1016/S0040-4039(00)60317-9

Sulfide-, sulfoxide-, and sulfone- containing C₂-symmetric peptide analogs were obtained stereospecifically starting from phenylalanine. The compounds were evaluated as potential HIV-protease inhibitors and found to be inactive within the limit