CHEMISTRY OF 4-MEMBERED CYCLIC NITRONES (2,3-DIHYDROAZETE 1-OXIDES); A NOVEL ONE-STEP SYNTHESIS OF N-ACETOXY β-LACTAMS

Article abstract of DOI:10.1016/S0040-4039(01)90262-X

2,3-Dihydroazete 1-oxide 1 reacts at room temperature with base, acid and lead tetraacetate to give the 5-hydroxyisoxazolidines 4a and 4b, the 6H-1,2-oxazin-6-one 7 and the N-acetoxy β-lactam 8, respectively; the reaction with lead tetraacetate represents